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Scientist/Sr. Scientist, Phage Display (San Diego, CA)

  • As a key member of the Biology Department, this position will contribute to the CovX portfolio by developing, implementing assays for high throughput protein/peptide screening. The position will select and screen for protein binding peptides using phage display as a primary tool. The position is also expected to advance peptide screening technologies beyond the phage display. The position will apply appropriate methods and instruments to evaluate compounds at different development stages. This position will work across therapeutic areas and discovery teams, making contributions to multiple efforts. A deep understanding of protein structure and state of the art knowledge of current technologies to characterize protein/protein interaction is required. Experience in structure modeling and protein design is plus.

    Qualifications:

    The successful applicant will be a highly motivated scientist with a proven track record in peptide/protein engineering and must have a minimum of two years of post-doctoral experience in an academic or industry setting, and a minimum of two years of recent experience in phage display technology or other display technologies.

    The candidate should have a PhD in biochemistry, molecular biology, chemical engineering or a relevant biological science. Familiarity with peptide screening and affinity maturation, and interpretation of computational modeling of peptide-antigen interactions would be useful. Significant experience with molecular cloning technologies, with extensive experience in protein engineering is required. Knowledge and experience in vivo phage panning is plus.

    The qualified individual must be a team player with the ability to multitask and work with several small teams simultaneously. Communication skills as well as technical expertise are keys to the success of this position. The candidate must have the ability to collaborate with colleagues throughout the organization in research functions i.e., bio-informatics, protein and cell sciences and structural biology. The candidate also should have strong computer skills, including development of automation routines and manipulation of large data sets in spreadsheet or database form.

    Please submit resumes for Requisition #940946 to www.pfizer.com

    Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act.

    All applicants must have authorization to work for Pfizer in the U.S. In certain circumstances it may be advantageous to Pfizer to support the application(s) for temporary visa classification and/or sponsor applications for permanent residence so that a foreign national colleague can accept or remain in a work assignment in the U. S.

    For certain classes of temporary visas, the resulting work authorization may be specific to Pfizer and the specific job and/or work site. Pfizer may at its business discretion decide to or refrain from obtaining, maintaining and/or extending the temporary visa status and/or sponsoring a colleague for permanent residency and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the colleague’s long-term prospects for securing lawful permanent residence, among other reasons.

    Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authorized to work for Pfizer in the U.S. and, if so, whether that authorization permits them to work in the job they seek. In no case should Pfizer’s support of a colleague’s temporary visa application or sponsorship of a colleague for permanent residence be construed to guarantee success of that application or amend or otherwise invalidate the “at-will” employment relationship between the colleague and Pfizer.

    Throughout our 153 years, a legacy of caring for others has been at the heart of everything we do at Pfizer. This commitment is no less important when it comes to our employees. Pfizer wants to ensure that employees have resources to help them develop and succeed both in their careers and personal lives. One way we can achieve this is through our comprehensive benefits program, which offers employees and their eligible dependents the variety and flexibility to help address their needs at different stages in life.

    CovX is a biotechnology unit within Pfizer’s Biotherapeutic Research and Development division located in San Diego, CA. Since its founding, CovX has made advances toward building a portfolio of clinical candidates. We use our proprietary technology to rapidly discover and develop long-acting biological therapeutics. The CovX technology unites the therapeutic attractiveness of peptides with the beneficial properties of antibodies, resulting in a new biopharmaceutical called a CovX-Body. The highly flexible nature of our technology enables us to identify high-value biological targets, efficiently create CovX-Bodies, and expeditiously move candidates to pre-clinical development and clinical evaluation.

    To apply for this position, please CLICK HERE

    ARBPFZ4144-762680

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